The Danish Molecular Biomedical Imaging Center (DaMBIC) is located at the University of Southern Denmark, Odense, Denmark.

The DaMBIC core facility provides access to state-of-the-art microscopy equipment, training and assistance required for the whole range of light microscopy for imaging specimens ranging from single molecules to cells and tissue. Exemplary case studies:

• Live cell imaging
• Diffusion in skin tissue
• Transport measurements in cells and membranes
• Cancer diagnostics
• Super-resolution of tight junction proteins
• Multi-photon imaging of resistance arteries
• Membrane imaging
• Characterization of organic LEDs and nanostructures
• Co-localization studies
• Food analysis
• Calcium ions and pH measurements in tissue and cells
• Automated image acquisition and analysis

Additionally we provide access to software and expertise in image data analysis and microscopy education.

PhD students, postdoctoral researcher, scientific staff and external academic and industry affiliated users may access our microscopes after a training by the DaMBIC superusers.

Equipment:

General widefield fluorescence microscopy with Nikon Ti or Ti-2 Eclipse using Nikon NIS Elements
Confocal microscopy on one of the 2 following microscopes: Nikon A1 and Leica SP8
STED (STimulated Emission Depletion microscopy) on one of 3 microscopes:
Leica SP8 STED (and CARS)
Abberior STED
Nikon 2 photon STED (home built)
SIM (Structued Illumination Microscopy)
STORM (STochastic Optical Reconstruction Microscopy)
CARS (Coherent anti-Stokes Raman microscopy)
Spinning disk microscopy (fast image acquisition for live cell imaging)
TIRF (Total Internal Reflection Fluorescence microscopy)
FLIM (Fluorescence Lifetime IMaging)
FCS (Fluorescence Correlation Spectroscopy)
Two-photon microscopy
RICS (Raster Imaging Correlation Spectroscopy)
AFM (Atomic Force Microscopy)

Soon to come: Abberior minFLUX